Re: Packer Fan Here
As a Packers fan, you'll be fine, just ignore any extremely drunk morons if you come across them. Most Steelers fans have a lot of respect for the NFC North teams (except for the Lions...obviously lol).
As everyone has already mentioned, go to Primanti's (in the Strip), you won't regret it!
If you're looking for a good nightlife scene I recommend the South Side (Carson Street). Honestly, any bar down there is a good time...my favorite is the Tiki Lounge though or the Smiling Moose (if you like a good metal bar lol).
If you want something more on the clubby side, go down to Station Square or the Strip District.
For touristy stuff, there's the Inclines, Point Park, any of the Carnegie Museums (the Science Center is my fave), the Western Pennsylvania Sports History Center (in the Strip District) and a ton more...just check out Pittsburgh.com for more info.
Hope you enjoy your trip and the game!