Not at much as Trent Edwards, apparently. 4 RTP penalties have been called in favor of the Bills.
3 have been called in favor of New England, and 3 against New England.
It's based on what he was capable of when he had the benefit of knowing, thanks to his coach, the opposing defensive plays.
Now that he's playing on a level field (although still in the most QB-friendly system in the league), here's where he's ranking:
Yep, you're right. He threw for as many as 28 touchdowns in a season thanks to "knowing the defensive plays".
Then in 2007, right after he no longer has this "advantage", he only throws for 50 touchdowns.